Genetics of model organisms
C. elegans
- Cell signaling via receptor tyrosine kinases
- Cell migration guidance mechanisms in the nematode C. elegans
My research focuses on understanding the fundamental mechanisms that control how complex, multicellular animals develop from single-cell fertilized eggs, a field known as Developmental Biology. We use molecular and genetic approaches in the model organism C. elegans to understand how cells within multicellular animals “talk” with each other to generate and maintain their normal structures and functions. Diseases such as cancer and a wide range of other pathologies arise from aberrations in the normal functioning of these processes. My specific areas of focus have concentrated on analyzing the cell-to-cell signaling mechanisms that guide migrating cells to their proper targets and that mediate fibroblast growth factor (FGF) signaling processes. The high degree of conservation of structure and function during metazoan evolution makes our findings in this organism applicable to our general understanding of biology, human biology and disease.
B.S. in Molecular Biophysics and Biochemistry, Yale University
Ph.D. in Biochemistry, University of California, Berkeley
Postdoctoral research: Massachusetts Institute of Technology. Advisor: Dr. H. Robert
Horvitz
Lo, T.-W., Bennett, D.C., Goodman, S.J., and Stern, M.J. (2010). Caenorhabditis elegans fibroblast growth factor receptor signaling can occur independently of the multi-substrate adaptor FRS2. Genetics 185: 537-547. PMID: 20308281
Kam, N., Kugler, H., Marelly, R., Appleby, L., Fisher J, Pnueli, A., Harel, D., Stern, M.J., Hubbard, E.J. (2008). A scenario-based approach to modeling development: a prototype model of C. elegans vulval fate specification. Dev. Biol. 323: 1-5. PMID: 18706404
Goodman, S.J., Branda, C.S., Robinson, M.K., Burdine, R.D. and Stern, M.J. (2003). Alternative splicing affecting a novel domain in the C. elegans EGL-15 FGF receptor confers functional specificity. Development 130: 3757-3766 PMID: 12835392
Mihaylova, V.T., Borland, C.Z., Manjarrez, L., Stern, M.J., and Sun, H. (1999). The PTEN tumor suppressor homolog in C. elegans regulates longevity and dauer formation in an insulin-receptor like signaling pathway. Proc. Natl. Acad. Sci. U.S.A. 96: 7427-7432. PMID: 10377431
Burdine, R.D., Branda, C.S. and Stern, M.J. (1998). EGL-17(FGF) expression coordinates the attraction of the migrating sex myoblasts with vulval induction in C. elegans. Development 125: 1083-1093. PMID: 9463355
Clark, S.G., Stern, M.J., and Horvitz, H.R. (1992). C. elegans cell-signalling gene sem-5
encodes a protein with SH2 and SH3 domains. Nature 356: 340-344. PMID: 1372395
Thomas, J.H., Stern, M.J. and Horvitz, H.R. (1990). Cell interactions coordinate the
development of the C. elegans egg-laying system. Cell 62: 1041-1052. PMID: 1821851
Stern, M.J., Ames, G.F.-L., Smith, N.H., Robinson, E.C. and Higgins, C.F. (1984). Repetitive Extragenic Palindromic Sequences: A major component of the bacterial genome. Cell 37: 1015-1026. PMID: 6378385
Room BBH 358B
91Porn
5500 North St. Louis Avenue
Chicago, IL 60625
United States
B.S. in Biology, 91Porn
Born in Celaya, Guanajuato, and raised in Chicago, I recently graduated with a bachelor's in Biology from 91Porn. I always knew I wanted to major in biology but didn’t know what to do with the degree. Luckily a friend pointed me toward working with youth in nature for the Student Conservation Association. Later, I joined SCA’s All Women Crew and after four years spent a season leading restoration projects for the Chicago Park District. My current role is Naturalist for Gensburg-Markham Prairie, a 100-acre tallgrass prairie remnant that is an Illinois Nature Preserve and a National Natural Landmark.
I am passionate about equitable access to nature. I hope to use my community engagement experience to bring more visitors to Gensburg-Markham Prairie from the surrounding communities and from across the city. I enjoy connecting with people and building bridges between communities of color and nature. I am very happy to have joined the Biology Department's team to preserve the prairie and include different groups of people in the process.
B.S. in Biology, 91Porn
Sara is an alumna of NEIU, where she completed a bachelor's degree in Biology and a minor in Environmental Studies. During her time here as an undergraduate she researched diatoms and the epizoic community of microscopic organisms living on the shells of captive snapping turtles. Sara thrived with the experiences brought to her by doing research at NEIU and wants to help students take advantage of the resources of the Biology Department so they can continue to grow as biologists and help others better understand the world we're living in.
Room BBH 358C
91Porn
5500 North St. Louis Avenue
Chicago, IL 60625
United States
B.S. in Biology, 91Porn
Israel is an alumnus of NEIU, where he completed a bachelor's degree in Biology. During his time here as an undergrad he researched Rhodiola integrifolia ssp. Leedyi genetic variability in various populations by using microsatellite data. Afterward, he worked on the Biology lab prep team, where he got to interact with both faculty and students. This experience inspired him to continue working at NEIU.
Room BBH 358G
91Porn
5500 North St. Louis Avenue
Chicago, IL 60625
United States
Since being at NEIU, I have focused on the ecology of prairies, particularly on the effect of fire on prairie communities.
Keywords: Prairies, Fire, Ecosystem Dynamics
Ph.D. from University of Illinois at Urbana-Champaign
M.S. from University of Illinois at Urbana-Champaign
B.S. from University of Illinois at Urbana-Champaign
Klaper, R., S. Frankel, and M.R. Berenbaum (1996). Anthocyanin content and UVB sensitivity in Brassica rap. Photochemistry and Photobiology, 63(6), 811-813.
Frankel, S., G.E. Robinson, and M.R. Berenbaum. Antioxidant capacity and correlated characteristics of 14 unifloral honeys. Journal of Apicultural Research. b1998.b37(1):27-31.
Frankel, S., & Berenbaum, M. (1999). Effects of Light Regime on Antioxidant Content of Foliage in a Tropical Forest Community 1. Biotropica, 31(3), 422-429.
Room BBH 358B
91Porn
5500 North St. Louis Avenue
Chicago, IL 60625
United States
M.S., 91Porn
B.S., Purdue University
Sanchez, J.C., Carrillo, M., Pandey, S., Noda, M., Aldama, L., Feliz, D., Claesson, E., Wahlgren, Y., Tracy, G., Duong, P., Nugent, A.C., Field, A., Šrajer, V., Kupitz, C., Iwata, S., Nango, E., Tanaka, R., Tanaka, T., Fangjia, L., Tono, K., Owada, S., Westenhoff, S., Schmidt, M., and Stojković, E.A. (2019) "" Structural Dynamics. 6: 054701.
Woitowich, N.C., Halavaty, A.S., Waltz, P., Kupitz, C., Valera, J., Tracy, G., Gallagher, K.D., Claesson, E., Nakane, T., Pandey, S., Nelson, G., Tanaka, R., Nango, E., Mizohata, E., Owada, S., Tono, K., Joti, Y., Nugent, A.C., Patel, H., Mapara, A., Hopkins, J., Duong, P., Bizhga, D., Kovaleva, S.E., St. Peter, R., Hernandez, C.N., Ozarowski, W.B., Roy-Chowdhuri, S., Yang, J., Edlund, P., Takala, H., Ihalainen, J., Brayshaw, J., Norwood, T., Poudyal, I., Fromme, P., Spence, J.C.H., Moffat, K., Westenhoff, S., Schmidt, M., and Stojković, E.A. (2018) "" IUCrJ. 5: 619-634.
Björling, A., Berntsson, O., Takala, H., Gallagher, K.D., Patel, H., Gustavsson, E., St. Peter, R., Duong, P., Nugent, A., Zhang, F., Berntsen, P., Appio, R., Rajkovic, I., Lehtivuori, H., Panman, M.R., Hoernke, M., Niebling, S., Harimoorthy, R., Lamparter, T., Stojković, E.A., Ihalainen, J.A., Westenhoff, S. (2015) .” Journal of Physical Chemistry Letters. 6: 3379–3383.
Room BBH 358 B
91Porn
5500 North St. Louis Avenue
Chicago, IL 60625
United States
Keywords: spite, violence, dehumanization, animal behavior
Ph.D. in Chronobiology and Protozoology from the University of Toronto
B.S. in Biology from 91Porn
A Totally, Unabashedly Incomplete Book About Bugs (Prairie House Gallery Press, 2018)
Room BBH 352B
91Porn
5500 North St. Louis Avenue
Chicago, IL 60625
United States
Conservation biology
Restoration ecology
M.S. in Plant Biology and Conservation from Northwestern University
B.A. in Environmental Studies from Knox College
Yost, J. L., L. M. Egerton-Warburton, K. M. Schreiner, C. E. Palmer, and A. E. Hartemink. (2016). Impact of Restoration and Management on Aggregation and Organic Carbon Accumulation in Urban Grasslands. Soil Sci. Soc. Am. J. 80:992-1002. doi:10.2136/sssaj2015.10.0383
Middleton, E. L., S. Richardson, L. Koziol, C.E. Palmer, Z. Yermakov, J. A. Henning, P. A. Schultz, and J. D. Bever. (2015). Locally adapted arbuscular mycorrhizal fungi improve vigor and resistance to herbivory of native prairie plant species. Ecosphere 6(12):276. doi:10.1890/ES15-00152.1
Yost, J., C. Palmer, and L. M. Egerton-Warburton. (2014). The contribution of soil aggregates to carbon sequestration in restored urban grasslands. In: A. Hartemink and K. McSweeney (Eds.) Progress in Soil Science Series: Soil Carbon (147-154). Heidelburg, Germany: Springer.
Room BBH 352G
91Porn
5500 North St. Louis Avenue
Chicago, IL 60625
United States
